Antidiabetic effects of ethanolic flower extract of Hibiscus Rosa sinensis (L) on alloxan induced diabetes in hyperlipidaemic experimental Wister rats (WNIN)
- Abhijeet Ghosh
- Dr. Abhijit Dutta
Alloxan, antidiabetic, hyperlipidemia, lipoproteins, Hibiscus rosa sinensis
Diabetes mellitus is one of the common metabolic disorders across the globe. Many lipoprotein abnormalities are seen in the untreated, hyperglycemic diabetic patients. This disease affects around 2.8% of the world's population and is likely to cross 5.4% by the year 2025. The use of herbal medicines for curing various ailments have been known since time in memorial and the herbal extracts have become a growing part of modern medicine. H. rosa sinensis has been used for the treatment of a variety of diseases. It is an easily available plant for natural remedies. The present study was undertaken to investigate the antidiabetic effects of the ethanolic Hibiscus flower extract in diabetes induced Wister rats which have been made hyperlipidaemic by feeding them with high fat diet.The serum blood glucose levels and lipid profile was found to be significantly increased in the hyperlipidaemic diabetic rat models while the level of plasma insulin was lowered. Treated groups administered with Hibiscus flower extract showed changes in the above biochemical parameters and it was found that among the three doses, 500 mg/kg showed the best result when compared to the other two doses. HRSFE exhibited potential antidiabetic against HFD fed alloxan induced diabetic Wister rats.
Abhijeet Ghosh, Dr. Abhijit Dutta. "Antidiabetic effects of ethanolic flower extract of Hibiscus Rosa sinensis (L) on alloxan induced diabetes in hyperlipidaemic experimental Wister rats (WNIN)".INTERNATIONAL JOURNAL OF ENGINEERING DEVELOPMENT AND RESEARCH ISSN:2321-9939, Vol.5, Issue 4, pp.674-679, URL :https://rjwave.org/ijedr/papers/IJEDR1704109.pdf
Volume 5 Issue 4
Pages. 674-679
