FORMULATION AND EVALUATION OF PHARMACEUTICAL AQUEOUS GEL OF CITRUS AURANTIUM DULCIS (ORANGE) PEELS EXTRACT FOR MOUTH ULCER TREATMENT
- Manthan M. Thawkar
- Maroti M, Jeurkar
- Rajashree V. Lode
- Satish B. Kosalge
Mouth ulcer gel, Orange, Antimicrobial activity, Antiulcer activity, citrus aurantium dulcis.
The objectives of present investigation were to formulate and evaluate herbal gel for mouth ulcer treatment of dried powdered citrus aurantium dulcis (orange) peels extract. Herbal gel was prepared by using different concentration of powdered citrus aurantium dulcis and carbopol 934, propylene glycol as a gel base. Formulations were evaluated for various physical parameters. The formulated gel was transparent, homogeneous and had PH ranges from 7 to 7.5.Also this formulation showed acceptable rheological behavior with applicable spread ability and extrudability properties. Antimicrobial studies of gel showed excellent efficacy against staphylococcus aureus and Escherichia coli. From the experimental evidence of in-vitrostudies it was observed that powdered contain flavonoids so it showed significant antioxidantand antimicrobial activity. This herbal aqueous gel formulation was stable, safe and effective for the treatment of mouth ulcer.
Manthan M. Thawkar, Maroti M, Jeurkar, Rajashree V. Lode, Satish B. Kosalge. "FORMULATION AND EVALUATION OF PHARMACEUTICAL AQUEOUS GEL OF CITRUS AURANTIUM DULCIS (ORANGE) PEELS EXTRACT FOR MOUTH ULCER TREATMENT".INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH ISSN:2455-2631, Vol.8, Issue 1, pp.1215 - 1218, URL :https://ijsdr.org/papers/IJSDR2301193.pdf
Volume 8 Issue 1
Pages. 1215 - 1218
